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MASLD AI 06:48 AM
November 2025
Learn how to confidently approach autoimmune cholestatic liver diseases in this high-yield talk from Ann Moore, NP, at Arizona Liver Health. She breaks down practical diagnosis and management of primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC)—from simple diagnostic algorithms (ALP, AMA, MRCP) and treatment goals like deep biochemical remission, to first- and second-line options with UDCA and newer agents such as FXR and PPAR agonists. Perfect for hepatology APPs and clinicians looking to optimize outcomes, manage pruritus and bone disease, and stay current on emerging trials and therapeutic targets in PBC and PSC.
Related Webcast
Webcast: MASLD Pharmacotherapy With Patrick Horne
September 2025
Join Patrick Horne, NP for a clear, clinic-ready overview of MASLD/MASH pharmacology—from the lifestyle backbone to cardiometabolic risk reduction and liver-directed therapies. Patrick breaks down where GLP-1 receptor agonists fit, reviews evidence and patient selection for vitamin E and pioglitazone, and spotlights resmetirom—the first FDA-approved THR-β agonist for non-cirrhotic MASH with F2–F3 fibrosis—including mechanism, key MAESTRO-NASH outcomes, common AEs (nausea/diarrhea), and practical drug–drug interactions. Walk away with a step-by-step approach to selecting therapy, setting measurable lifestyle goals, and using NITs to monitor response and guide duration—so you can confidently tailor treatment and improve outcomes.
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Webcast: MASLD Pharmacotherapy With Jill Olmstead
September 2025
Join Jill Olmstead, DNP from Providence Health for a practical, clinician-focused overview of MASLD pharmacotherapy and new treatment horizons for hepatic steatosis. This session in the GHAPP MASLD & MASH Community Network covers the shift in nomenclature, why care must be multidisciplinary (obesity, type 2 diabetes, dyslipidemia, hypertension, cardiovascular risk), and how to stage disease with FIB-4, noninvasive tests, and FibroScan before initiating therapy. Jill reviews lifestyle and weight-loss strategies, GLP-1 receptor agonists—their mechanisms, common GI side effects, and peri-procedure considerations due to delayed gastric emptying—plus where vitamin E and pioglitazone do and don’t fit today. She also walks through practical use of resmetirom for non-cirrhotic MASH with F2–F3 fibrosis (labs to order, monitoring, drug–drug interactions, and setting expectations alongside diet and exercise). If you’re a GI/hepatology clinician, APP, or primary-care partner looking to streamline risk reduction, staging, and evidence-based therapy for MASLD/MASH, this talk delivers step-by-step guidance you can use in clinic today.
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Webcast: MASLD Pharmacotherapy With Marcella Pomeranz
October 2025
In this educational session, Marcella Pomeranz, DNP, explores the evolving pharmacotherapy options for Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD) and Metabolic Dysfunction–Associated Steatohepatitis (MASH). Presented through the GHAPP MASLD Community Network and supported by Madrigal Pharmaceuticals, this talk reviews both established and emerging therapies—from GLP-1 receptor agonists and pioglitazone to vitamin E and the recently approved resmetirom (Rezdiffra). Marcella discusses practical considerations for treatment selection, dosing adjustments, and medication safety, along with strategies to combine pharmacologic therapy with diet, exercise, and lifestyle modification to slow fibrosis progression and improve liver outcomes.
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Webcast: Non-Invasive Testing With April Morris
July 2025
In this educational presentation, April Morris, NP—an experienced provider in both liver disease and endocrinology—guides viewers through the evolving landscape of non-invasive testing (NITs) for diagnosing and managing patients with MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease) and MASH. Using the case of a 65-year-old male with metabolic co-morbidities and suspected liver disease, Morris reviews how to effectively apply tools like the FIB-4 score, ELF test, and FibroScan (VCTE) to assess fibrosis risk and stratify patients. She compares imaging modalities including transient elastography, MR elastography (MRE), and shear wave elastography, offering practical considerations such as patient eligibility, test accuracy, and insurance barriers. The discussion emphasizes the importance of interpreting NITs within clinical context—highlighting how to determine risk, guide patient counseling, and establish a follow-up plan for low-risk patients. This session also reinforces the role of primary care in longitudinal liver health management and directs providers to resources available through the GHAPP MASLD & MASH Community Network.
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Webcast: Comparing F3 and F4 Fibrosis With Kristina Tuesday Werner
October 2025
Tuesday Werner, NP, explains why accurately identifying F3 vs F4 fibrosis is critical in patients with MASLD/MASH. Using real patient case comparisons, she highlights how non-invasive tests like FIB-4, FibroScan, and ELF help determine disease severity, guide treatment, and reduce the need for biopsy. Tuesday reviews how care strategies differ—F3 patients focus on aggressive metabolic control and fibrosis monitoring, while F4 (cirrhosis) requires HCC surveillance, closer specialist follow-up, and potential transplant evaluation.
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Webcast: Lifestyle Management With Lavinia Iordache
September 2025
In this MASLD Community Network session, Lavinia Iordache uses a real-world case to show how to recognize and manage fatty liver disease with a lifestyle-first approach. She reviews the clinical pathway for at-risk patients (hypertension, dyslipidemia, diabetes, central adiposity), the role of non-invasive tests, and why indeterminate results often require a second modality. The talk clarifies alcohol distinctions and emphasizes that early staging and referral can change prognosis. Practical guidance includes culturally sensitive nutrition counseling (prioritizing the Mediterranean diet), realistic weight-loss targets, and tailored exercise plans—both aerobic and resistance training improve hepatic fat via different pathways. Lavinia also covers behavior strategies and cautions on one-size-fits-all tactics. You’ll leave with a clear, compassionate framework to help patients sustain lifestyle change, optimize cardiometabolic risk, and monitor disease progression over time.
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Webcast: MASLD Basics With Melissa Franco
August 2025
Join Melissa Franco, PA-C, from the University of Miami for a comprehensive review of MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease) and the 2023 nomenclature updates replacing NAFLD and NASH. Presented through the GHAPP MASLD Community Network and sponsored by Madrigal Pharmaceuticals, this session covers the spectrum of steatotic liver disease, including MASLD, MASH, MetALD, alcohol-related liver disease (ALD), and other causes of hepatic steatosis. Learn how to diagnose MASLD using imaging, cardiometabolic risk criteria, and how to exclude other causes like alcohol use, medications, and genetic disorders. Melissa explains how to risk stratify patients using FIB-4, FibroScan, and ELF testing, and when to consider referral to hepatology, especially for patients at intermediate or high risk for advanced fibrosis. The talk also explores global prevalence, natural history, disease progression to cirrhosis and HCC, and highlights the importance of identifying and managing patients with F2–F4 fibrosis, now classified as at-risk MASH. Through a real-world case study, viewers are guided on how to perform a thorough MASLD workup and assess patients for pharmacotherapy, lifestyle counseling, and surveillance protocols. Whether you are in primary care, GI, or endocrinology, this session is an essential resource for early diagnosis and comprehensive management of fatty liver disease in today’s clinical practice.
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Webcast: Comparing F3 and F4 Fibrosis With Erin Tanner
July 2025
Join Erin Tanner, NP from Gastro Health in Birmingham, Alabama, for a practical and in-depth exploration of how to differentiate and manage patients with F3 versus F4 fibrosis in the setting of MASLD (Metabolic Dysfunction-Associated Steatotic Liver Disease) and MASH. This session, part of the MASLD & MASH Community Network, features two detailed case studies—Sam A and Sam B—who share identical comorbidities but diverge in fibrosis stage, illustrating how non-invasive testing (NITs) can guide diagnosis and treatment. Erin walks through the clinical application of tools like FIB-4, FibroScan (VCTE), ELF test, and CAP score, emphasizing the importance of interpreting lab and imaging results in context. The discussion covers key decision points, including when to initiate pharmacologic therapy like resmetirom (Rezdiffra), how to determine eligibility for HCC surveillance, and when to consider liver biopsy. She also addresses common challenges in community GI settings, such as incidental fatty liver findings, elevated ferritin levels, and the limitations of FIB-4 in older or diabetic patients. Whether you're in hepatology, gastroenterology, or primary care, this talk offers actionable insights on fibrosis staging, lifestyle counseling, and long-term monitoring in patients with MASLD and MASH.
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Webcast: MASLD vs MetALD With Lindsay Pratt
October 2025
Learn from Lindsay Pratt, PA-C at the University of Colorado Hepatology Clinic, as she explores the evolving landscape of metabolic dysfunction–associated steatotic liver disease (MASLD) and metabolic dysfunction and alcohol-associated liver disease (MetALD) in this comprehensive, case-based discussion. Drawing on over 15 years of experience in hepatology and liver transplantation, Lindsay walks through real-world evaluation and management of a 52-year-old patient with hepatic steatosis, highlighting key diagnostic clues, lab interpretations, and the importance of incorporating objective biomarkers such as PEth testing to accurately assess alcohol use. This educational session provides clarity on differentiating MASLD, MASH, and MetALD, interpreting FibroScan results, and addressing cardiometabolic risk factors like obesity, hypertension, and hyperlipidemia. Pratt also emphasizes practical treatment strategies, including lifestyle modification, GLP-1 therapy, and alcohol cessation counseling, along with considerations for emerging therapies like resmetirom (Rezdiffra). APPs and hepatology clinicians will gain valuable insights into patient communication, disease classification, and evidence-based management approaches that can help slow progression, reduce fibrosis risk, and optimize liver outcomes.
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Webcast: Non-Invasive Testing With Stacie Egan
October 2025
Stacie Egan, FNP-C, discusses how non-invasive testing is transforming the way clinicians evaluate and manage MASLD/MASH. Using a real patient case, she explains how to interpret key tools like FIB-4, ELF, FibroScan (VCTE), and MR elastography to assess liver stiffness, steatosis, and fibrosis severity. Stacie also highlights practical considerations for accurate testing, when to order secondary assessments, and how to combine results with clinical judgment for optimal patient care. Learn how non-invasive diagnostics guide treatment decisions, support early intervention, and improve outcomes in metabolic liver disease.
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