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MASLD AI 06:59 AM
November 2025
Join Anna Marie Hefner, RN and Renee Pozza, FNP-BC from Southern California Liver & GI Centers for a practical, case-based deep dive into advanced MASLD/MASH—what F3 vs F4 (cirrhosis) really means for staging, treatment, and surveillance. Using a 55-year-old patient scenario, they walk through interpreting FIB-4, FibroScan® (kPa + CAP), ELF, and routine labs; when to add ultrasound + AFP for HCC surveillance, and when to scope for esophageal varices. You’ll hear how they structure follow-up (from biweekly check-ins early to every 3 months), tailor diet and exercise to real-world habits, incorporate GLP-1s for weight and metabolic control, and consider resmetirom for eligible F2–F3 patients (not F4). The session also covers when to escalate to colonoscopy for alternative bleeding sources, and how to alternate US with triphasic CT/MRI in high-risk patients. Perfect for GI/hepatology APPs looking for a clear, actionable framework to manage fibrosis progression and optimize outcomes.
Related Webcast
Webcast: Non-Invasive Testing With Brian Lam
August 2025
Join Brian Lam, PA-C, Associate Medical Director of Research at Inova’s Liver and Obesity Research Program and Chair of the Global NASH/MASH Council’s PA Committee, for a masterclass on non-invasive testing (NITs) in the evaluation of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and MASH, presented through the GHAPP MASLD/MASH Community Network and sponsored by Madrigal Pharmaceuticals. In this dynamic and case-based session, Brian outlines a practical, step-by-step approach to identifying patients at risk for advanced fibrosis, using tools like FIB-4, ELF, FibroScan (VCTE), and MR Elastography. He walks through the critical cutoffs, diagnostic performance, limitations, and how to interpret imaging and lab-based scores in real-world hepatology and primary care settings. You'll learn how to apply AGA and AASLD clinical algorithms, the importance of staging patients with diabetes and metabolic syndrome, and how to distinguish low-risk MASLD from at-risk MASH. Brian also shares best practices for TE reliability, quality control, and using NIT combinations like FAST, MAST, and MEFIB for accurate diagnosis. With clear visuals, expert insights, and actionable takeaways, this session is an essential update for APPs, GI, hepatology, and primary care providers managing fatty liver disease in 2025 and beyond.
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Live From GHAPP National: Abnormal Liver Chemistry Workup
November 2025
In this session, Jeremy Davis, ACNP from Shreveport, Louisiana, breaks down a practical, step-by-step approach to evaluating abnormal liver chemistries. Using a real patient case, he reviews how to interpret ALT, AST, ALP, bilirubin, MCV, and GGT patterns; when to suspect hepatocellular, cholestatic, or mixed injury; and how to build an efficient differential using history, medications, alcohol assessment, and key labs (viral hepatitis panel, autoimmune markers, iron studies, Wilson disease testing, alpha-1 antitrypsin phenotype). He also highlights the role of ultrasound, MRCP, non-invasive fibrosis tests (FIB-4, ELF, VCTE), and when biopsy is needed. A practical, clinic-ready guide for APPs and clinicians assessing elevated liver enzymes and differentiating MASLD, alcohol-related disease, DILI, and other common etiologies.
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Webcast: MASLD vs MetALD With Milly Ng
October 2025
Milly Ng explores the intersection of metabolic dysfunction–associated steatotic liver disease (MASLD) and alcohol-related liver disease (ALD)—known as MetALD. Through a real-world patient case, she explains how metabolic risk factors like obesity, hypertension, and dyslipidemia interact with alcohol use to accelerate liver damage, fibrosis, and HCC risk. Learn how to identify and manage MetALD using FibroScan, PEth testing, and evidence-based strategies including lifestyle modification, alcohol cessation, and emerging therapies like resmetirom.
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Webcast: MASLD Basics With Punam Punja
October 2025
Punam Punja, PA provides an overview of MASLD basics, explaining the 2023 terminology update that replaced NAFLD/NASH with MASLD/MASH and introduced MetALD for patients with metabolic dysfunction and alcohol exposure. Learn how to diagnose MASLD using imaging, metabolic risk factors, and non-invasive tests such as FIB-4, ELF, and FibroScan—plus when to refer for hepatology evaluation or liver biopsy. Punja also reviews staging, HCC surveillance, and practical lifestyle recommendations for patients at risk of fibrosis and cirrhosis.
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Webcast: Non-Invasive Testing With Allison Moser
November 2025
In this educational session from the GHAPP MASLD Community Network, Allison Moser, NP, from Rush University Medical Center, explains how non-invasive testing (NITs) is changing the way clinicians assess and manage metabolic-associated steatotic liver disease (MASLD) and metabolic-associated steatohepatitis (MASH). Through a real patient case study, she reviews key diagnostic tools like FIB-4, ELF, FibroScan, and MRI elastography, highlighting how each test helps identify fibrosis risk, reduce the need for biopsy, and guide patient management. Learn how to interpret test results, understand their limitations, and apply them in everyday clinical practice to improve liver health outcomes. #MASLD #MASH #Fibrosis #NonInvasiveTesting #FIB4 #ELFTest #FibroScan #MRIelastography #LiverHealth #Hepatology #APPeducation
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Webcast: Non-Invasive Testing With Jeremy Davis
September 2025
Join Jeremy Davis, NP, for a clear, clinic-ready walkthrough of non-invasive testing for MASLD/MASH. Using a real case, Jeremy shows how to risk-stratify patients starting with FIB-4 and when intermediate scores should trigger liver stiffness measurement. Learn practical cutoffs, image-quality checkpoints (valid measures, IQR/median), and common confounders (ALT/AST flares, cholestasis, recent meals, alcohol, obesity, ascites) that can overestimate stiffness. He contrasts pros/cons of VCTE vs. MRE, explains how to pair ELF with FibroScan, and maps decisions to AGA/AASLD-aligned pathways—who to refer, who to monitor, and how often to re-stage. The session closes with actionable counseling on lifestyle, weight loss targets, and cardiometabolic risk control to slow fibrosis progression while minimizing unnecessary biopsies.
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Webcast: MASLD vs MetALD With Chantil Jeffreys
September 2025
Chantil Jeffreys, FNP at Gastro One, offers a clear, case-based overview of metabolic dysfunction–associated steatotic liver disease (MASLD), MASH, and mixed-etiology MET-ALD. Using a common clinic scenario, she explains how to recognize steatotic liver disease, why accurate alcohol history matters, and how non-invasive tools (e.g., FibroScan for stiffness and CAP, alcohol biomarkers like PEth/EtG) can clarify what’s driving liver injury. You’ll get practical guidance on lifestyle therapy—Mediterranean-style nutrition, sustainable weight loss, and regular aerobic plus resistance exercise—along with when to consider medications, specialist referral, and HCC surveillance. Ideal for APPs and GI clinicians seeking a simple, patient-centered approach to preventing progression from fatty liver to advanced fibrosis and cirrhosis.
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Webcast: Non-Invasive Testing With Kelly Smeester
August 2025
Join Kelly Smeester, MMS, RD, PA-C, from South Denver Gastroenterology, for an in-depth discussion on the latest tools and strategies in non-invasive liver disease assessment, presented through the GHAPP MASLD Community Network. This evidence-based session walks viewers through a case study of a patient with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and explores the full range of non-invasive testing modalities used to evaluate liver fat, stiffness, and fibrosis risk. Kelly breaks down the utility of key tests including FIB-4, ELF Score, FibroScan (VCTE), and MR Elastography, and compares their accuracy, accessibility, limitations, and clinical value. Learn how to interpret biomarkers such as CAP (Controlled Attenuation Parameter) and kPa (Kilopascals), how to navigate indeterminate FIB-4 results, and when to escalate to more advanced imaging like MRE. The session also provides insights into combined scoring models (FAST, MAST, MEFIB), real-world use cases, and how comorbidities and patient-specific factors (BMI, ALT, bilirubin, ascites) can impact test reliability. Whether you're managing early-stage fatty liver disease or advanced fibrosis, this session provides essential knowledge to guide accurate diagnosis, risk stratification, and long-term monitoring without a liver biopsy.
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Webcast: MASLD vs MetALD With Jeremy Davis
September 2025
In this MASLD Community Network talk, Jeremy Davis, NP, uses a real-world case to clarify how to differentiate MASLD from MetALD, interpret alcohol exposure, and stage disease with non-invasive tools. He explains standard drink equivalents (≈14 g ethanol) and why accurate histories plus objective biomarkers matter, then walks through labs and elastography (FibroScan kPa/CAP) showing F3 fibrosis with severe steatosis. You’ll learn a practical workflow to rule out alternative etiologies, quantify alcohol use, and understand how metabolic risk plus alcohol accelerates fibrosis and decompensation risk. Jeremy outlines counseling pearls (abstinence recommendations, Mediterranean-style diet, weight loss, activity), eligibility considerations for resmetirom in non-cirrhotic MASH (F2–F3), and when to start HCC surveillance. Watch to strengthen your staging, counseling, and treatment decisions for patients who fall along the MASLD–MetALD spectrum.
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Webcast: Non-Invasive Testing With Elizabeth Alqueza
August 2025
In this session, Elizabeth Alqueza, PA-C at Beth Israel Deaconess Medical Center, provides a comprehensive overview of non-invasive testing in patients with Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD) and MASH. Using a real clinical case, she explains how to evaluate patients with abnormal liver enzymes and steatosis on imaging, and how to apply widely used tools such as the FIB-4 score, ELF test, FibroScan (VCTE), CAP score, shear wave elastography, and MR elastography. Elizabeth highlights the strengths, limitations, and interpretation of each test, along with practical considerations like cost, accessibility, patient factors, and operator experience. She also reviews the MASLD care pathway, emphasizing how accurate staging with non-invasive tests helps identify at-risk patients with advanced fibrosis who need closer monitoring, lifestyle interventions, and specialty referral. This talk underscores the critical role of non-invasive assessment in preventing progression to cirrhosis, liver failure, and hepatocellular carcinoma.
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