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MASLD AI 07:17 AM
November 2025
Join Michelle Barnett, PA-C for a concise, case-based update on the new steatotic liver disease nomenclature—MASLD, MASH, and MetALD—and what it means for risk stratification and management. She walks through calculating FIB-4, interpreting FibroScan (kPa/CAP), and quantifying alcohol exposure (e.g., PEth) to differentiate metabolic-predominant from alcohol-associated disease. You’ll learn practical next steps: lifestyle and Mediterranean diet counseling, structured exercise goals, when to consider Resmetirom for F3 fibrosis, and why HCC screening now extends to F3. Perfect for APPs and clinicians looking to apply 2023+ consensus guidance in everyday hepatology practice.
Related Webcast
Live From GHAPP National: Abnormal Liver Imaging: What's Next?
November 2025
In this high-yield session, HoChong Gilles, NP from the Central Virginia VA Healthcare System, guides viewers through a practical approach to abnormal liver imaging and the challenge of incidental liver lesions. She reviews how to differentiate cystic versus solid liver lesions, outline key risk factors, and interpret enhancement patterns on ultrasound, CT, and MRI to distinguish benign findings—such as simple cysts, hemangiomas, FNH, and hepatic adenomas—from malignant lesions including hepatocellular carcinoma (HCC) and metastatic disease. Designed for APPs and clinicians who frequently encounter unexpected lesions on imaging, this concise overview provides clear strategies for knowing when to reassure, when to monitor, and when to escalate evaluation or referral.
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Webcast: MASLD vs MetALD With Jill Olmstead
November 2025
In this educational session, Jill Olmstead, DNP, from Providence Health in Southern California, reviews the new clinical guidelines for metabolic-associated steatotic liver disease (MASLD) and the emerging category MetALD—metabolic-associated liver disease related to alcohol use disorder. Through a case-based discussion, she explains how to evaluate patients with fatty liver disease, interpret key biomarkers like FIB-4 and FibroScan, and distinguish between metabolic and alcohol-related liver damage. Jill highlights the importance of weight loss, lifestyle modification, and alcohol cessation as essential interventions to reverse steatosis and fibrosis, and discusses the role of Resmetirom (Rezdiffra) as a newly approved therapy for patients with moderate to advanced fibrosis. This comprehensive overview helps clinicians and advanced practice providers apply updated MASLD and MetALD guidelines in everyday gastroenterology and hepatology practice.
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Webcast: MASLD vs MetALD With Milly Ng
October 2025
Milly Ng explores the intersection of metabolic dysfunction–associated steatotic liver disease (MASLD) and alcohol-related liver disease (ALD)—known as MetALD. Through a real-world patient case, she explains how metabolic risk factors like obesity, hypertension, and dyslipidemia interact with alcohol use to accelerate liver damage, fibrosis, and HCC risk. Learn how to identify and manage MetALD using FibroScan, PEth testing, and evidence-based strategies including lifestyle modification, alcohol cessation, and emerging therapies like resmetirom.
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Webcast: MASLD Basics With Edith Johannes
November 2025
Learn the fundamentals of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in this educational session featuring Edith Johannes, NP, a liver specialist at UCLA Health with over 17 years of experience in hepatology and liver transplantation. Supported by the GHAPP MASLD Community Network and Madrigal Pharmaceuticals, this session explores the new terminology and diagnostic criteria for MASLD—formerly known as NAFLD and NASH—and explains why these changes matter for both clinicians and patients. Viewers will gain a clear understanding of how to evaluate patients presenting with hepatic steatosis, distinguish MASLD from alcohol- or drug-induced liver injury, and apply key diagnostic tools such as FIB-4, ELF testing, and elastography to assess fibrosis progression. Johannes also discusses the clinical importance of ruling out overlapping conditions, recognizing metabolic risk factors, and identifying patients at risk for fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). Whether you’re new to hepatology or seeking a concise refresher, this talk provides a practical framework for diagnosing and managing MASLD in primary and specialty care.
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Webcast: MASLD Pharmacotherapy With Allison Moser
November 2025
Join Allison Moser, NP, hepatology nurse practitioner at Rush University Medical Center, for a comprehensive update on pharmacotherapy in MASLD and MASH. In this MASLD Community Network session, Allison reviews the evolving treatment landscape—from lifestyle and metabolic management to the latest FDA-approved medications. Learn how resmetirom, the first and only approved therapy for MASH with stage 2–3 fibrosis, works as a thyroid hormone receptor-β agonist to improve liver fat and fibrosis. Discover the growing role of GLP-1 receptor agonists such as semaglutide in MASH management, as well as key insights on vitamin E, pioglitazone, and metabolic risk reduction through diet, exercise, and comorbidity control. This evidence-based discussion highlights the latest clinical trial data, practice guidelines, and real-world considerations for advanced practice providers managing metabolic liver disease. #MASH #MASLD #LiverHealth #Hepatology #APPeducation #Resmetirom #Semaglutide #FattyLiverDisease #NASH #MetabolicHealth
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Webcast: MASLD Basics With Chantil Jeffreys
September 2025
In this MASLD/MASH Community Network “Basics” session, Chantil Jeffreys, FNP clarifies the new MASLD/MASH nomenclature, how to recognize metabolic criteria (obesity, dyslipidemia, hypertension, impaired glucose/A1C, low HDL), and when to rule out other causes (alcohol overlap, DILI, cryptogenic disease). She walks through a practical primary-care workflow: start with FIB-4, then risk-stratify with FibroScan or ELF, identify patients who need hepatology referral, and decide when liver biopsy is appropriate (discordant/indeterminate NITs, suspected concomitant disease, select older patients). The talk covers global prevalence, natural history and progression (F0→F4/cirrhosis→HCC), and why aggressive cardiometabolic risk reduction and appropriate surveillance matter. You’ll leave with a clear algorithm to stage disease, monitor over time, and communicate the MASLD/MASH shift to colleagues and patients.
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Webcast: MASLD Pharmacotherapy With Jonathan Yeh
August 2025
In this GHAPP MASLD Community Network Education Series, Jonathan Yeh, PA from Columbia University Irving Medical Center, reviews the latest advances in pharmacotherapy for MASLD (Metabolic Associated Steatotic Liver Disease) and MASH (Metabolic Associated Steatohepatitis). This presentation explores the evolution from NAFLD to MASLD, highlighting why metabolic dysfunction is central to disease progression. Jonathan discusses the role of lifestyle modification, GLP-1 receptor agonists (such as semaglutide and tirzepatide), vitamin E, pioglitazone, and bariatric surgery, while focusing on resmetirom—the first FDA-approved therapy for adults with non-cirrhotic MASH and moderate to advanced fibrosis. The session explains how resmetirom works as a thyroid hormone receptor beta agonist, its clinical trial evidence from the MAESTRO-NASH study, patient eligibility, safety considerations, drug–drug interactions, and monitoring recommendations. With ongoing studies and expanding treatment options, this discussion provides clinicians with practical strategies for managing MASLD and MASH, improving liver outcomes, and addressing the challenges of insurance access and long-term therapy.
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Webcast: MASLD Basics With Lindsay Yoder
September 2025
Lindsay Yoder, PA, Indiana University, delivers a clear primer on the new MASLD/MASH nomenclature and how it fits within the broader Steatotic Liver Disease (SLD) spectrum—including MetALD and alcohol-associated liver disease—so clinicians can label etiology correctly and tailor care. She walks through a practical primary-care algorithm: start with FIB-4 (use 1.3 and 2.67 cutoffs), then add ELF and/or VCTE/FibroScan (LSM and CAP) to risk-stratify fibrosis, refer when intermediate/high risk, and reserve biopsy for discordant cases. The session reviews staging (F0–F4), when to escalate to cirrhosis management and HCC/variceal surveillance, and highlights the impact of the first FDA-approved therapy (resmetirom) for MASH with F2–F3 fibrosis, alongside multidisciplinary lifestyle and cardiometabolic optimization. Perfect for APPs, PCPs, GI, and hepatology teams seeking a concise “basics to bedside” roadmap.
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Webcast: MASLD Basics With Gabriella McCarty
August 2025
In this educational session, Gabriella McCarty, NP-C at Oshi Health, shares practical insights into Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and MASH. Drawing from over 25 years of experience in GI, IBD, and hepatology, she explains how many fatty liver patients are discovered incidentally during workups for unrelated issues such as GERD or routine colonoscopy. Gabriella reviews the new global terminology (MASLD replacing NAFLD, MASH replacing NASH), outlines key metabolic risk factors that define MASLD, and walks through the role of non-invasive tests (FIB-4, FibroScan, ELF, ultrasound) in staging fibrosis. She emphasizes the importance of early detection, patient education, and primary care involvement in identifying at-risk individuals before progression to advanced fibrosis, cirrhosis, or liver cancer. This presentation highlights how MASLD can silently progress, why primary care and GI collaboration are critical, and the growing need for global awareness and prevention of progressive liver disease.
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Webcast: Non-Invasive Testing With Elizabeth Alqueza
August 2025
In this session, Elizabeth Alqueza, PA-C at Beth Israel Deaconess Medical Center, provides a comprehensive overview of non-invasive testing in patients with Metabolic Dysfunction–Associated Steatotic Liver Disease (MASLD) and MASH. Using a real clinical case, she explains how to evaluate patients with abnormal liver enzymes and steatosis on imaging, and how to apply widely used tools such as the FIB-4 score, ELF test, FibroScan (VCTE), CAP score, shear wave elastography, and MR elastography. Elizabeth highlights the strengths, limitations, and interpretation of each test, along with practical considerations like cost, accessibility, patient factors, and operator experience. She also reviews the MASLD care pathway, emphasizing how accurate staging with non-invasive tests helps identify at-risk patients with advanced fibrosis who need closer monitoring, lifestyle interventions, and specialty referral. This talk underscores the critical role of non-invasive assessment in preventing progression to cirrhosis, liver failure, and hepatocellular carcinoma.
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