Comparing F3 and F4 Fibrosis With Lindsay Yoder

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MASLD AI 03:58 AM

September 2025

In this in-depth educational session, Lindsay Yoder, PA from Indiana University in Indianapolis, walks through two detailed case studies to highlight the differences between advanced F3 fibrosis and F4 cirrhosis. Using real-world clinical data—including labs, FibroScan, ELF testing, and imaging—she explains how to stage patients with MASLD/MASH, interpret non-invasive fibrosis assessments, and tailor treatment strategies.

Viewers will learn how subtle differences in labs and imaging findings, such as thrombocytopenia and liver stiffness measurement, can shift a patient’s diagnosis from advanced fibrosis to cirrhosis. Lindsay also discusses the role of lifestyle interventions, multidisciplinary management, and therapeutic options like resmetirom and GLP-1s, as well as key monitoring strategies for hepatocellular carcinoma (HCC) surveillance and variceal screening.

Whether you’re a hepatology provider, an APP, or a clinician looking to sharpen your skills in managing MASLD/MASH, this case-based discussion provides practical insights you can apply in everyday practice.

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